Avances en el desarrollo de inmunización
contra el coronavirus: del SARS COVID-19
Advances in the development of immunization against
the coronavirus: from SARS COVID-19
Jennifer Pamela Picón Rodríguez
Consultorio particular, jennifer2436@hotmail.com,
https://orcid.org/0000-0003-4264-6208
Erika Aracely Pinos Vélez
Consultorio particular, eapv0612@hotmail.com,
https://orcid.org/0000-0002-0932-9991
Jessica Johana Álvarez Toapanta
Hospital Básico La Guadalupana-Ambato,
md.jessicaalvarez@gmail.com,
https://orcid.org/0000-0001-5692-2459
Juan Gonzalo Salinas Villacís
Hospital IESS de Ambato, juansv93@hotmail.com,
https://orcid.org/0000-0003-3736-0926
!
Dayana Lissette Miranda Espín
Centro de salud Sociovivienda 1,
dra.dayimiranda@gmail.com,
https://orcid.org/0000-0001-5073-3892
!
Guayaquil - Ecuador
http://www.jah-journal.com/index.php/jah
Journal of American health
Julio - Diciembre vol. 4. Num. 2 – 2021
24-33
Esta obra está bajo una Licencia Creative Commons
Atribución-NoComercial-CompartirIgual 4.0 Internacional.
RECIBIDO: 12 DE OCTUBRE 2020
ACEPTADO: 23 DE FEBRERO 2021
PUBLICADO: 4 DE JULIO
RESUMEN
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26
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ABSTRACT
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INTRODUCCIÓN!
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MATERIALES Y MÉTODOS
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29
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DISCUSIÓN
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$#8#!FA'!'<!2)23'(#!)%(A%7<>;)57!&'2#887<<'!<72!#%3)5A'8$72!=)8#<'2!JXIKC"#!':'53)=)&#&!&'!A%#!
=#5A%#!&'$'%&'!&'!2A!5#$#5)&#&!&'!)%&A5)8!A%#!8'2$A'23#!)%(A%'!$873'5378#@!$'87@!$78!7387!
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30
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31
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CONCLUSIONES
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L%!'23'!2'%3)&7!<#!*.*!8'57()'%&#%!FA'!2'!=#5A%'!57%38#!'<!*+,-./01!<7!#%3'2!$72)6<'C!
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REFERENCIAS
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